Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. Venofer is not for treating other forms of anemia not caused by iron deficiency. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. With this condition, you also have a low hemoglobin level. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Last reviewed . This test measures the amount of hemoglobin in your blood. Phosphorus also helps your nerves function properly. You may need extra iron because of blood loss during kidney dialysis. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. With IDA, you have low hemoglobin levels. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. However, side effects at the 150 mg dose may indicate that you might not . These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). What to Know About Iron Infusions for Anemia Treatment - GoodRx Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. In the US - Call your doctor for medical advice about side effects. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. You may report side effects to the FDA at 1-800-332-1088. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Venofer treatment may be repeated if iron deficiency reoccurs. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Does Daxxify Work Better Than Botox? I Tried The New Neurotoxin. 1 0 obj If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. If you have diarrhea while youre taking Injectafer, call your doctor. These changes could help improve your anemia on a long-term basis. Infusions should be administered over at least 15 minutes. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Why is the range so wide? In the second group, some people switched from taking iron by mouth to taking Injectafer. Does Venofer Vial interact with other medications? Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Its responsible for carrying oxygen throughout your body. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. ByDr. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. This product may contain inactive ingredients, which can cause allergic reactions or other problems. dizziness. People with IDA have low blood levels of hemoglobin. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Injectafer contains the active drug ferric carboxymaltose. Injectafer isnt available in a generic form. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Available for Android and iOS devices. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Many people using this medication do not have serious side effects. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Do not exceed 1,500 mg of iron per dosing course. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Some drugs may have another patient information leaflet. Youll receive doses of either drug by a healthcare professional at a medical facility. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Learn how to store and discard medical supplies safely. US residents can call their local poison control center at 1-800-222-1222. Its not known whether its safe to breastfeed while youre taking Injectafer. Your doctor will go over your VenAccess is a trademark of Vifor (International) Inc. Switzerland. (And Injectafer is used to treat IDA.) For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. (A class of medications describes a group of drugs that work in the same way.). Best food forward: Are algae the future of sustainable nutrition? Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. If you think there has been an overdose, call your poison control center or get medical care right away. Injectafer (ferric carboxymaltose): Side effects and more For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. After the infusion, you can drive yourself home and return to your usual activities. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Your doctor will determine the best dosage to fit your needs. With slow IV injection, the drug is given as a single, slow injection into your vein. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. These lists dont include all possible side effects. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. All rights reserved. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. This may lead to the person needing a higher dose compared to someone who is muchsmaller. And these two doses need to be separated by at least 7 days. (One treatment course includes two doses of the drug.) Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Then your body uses that iron to make hemoglobin and RBCs. Check with your pharmacist if you have questions about the best way to throw out drugs. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Details. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. What Is the Cost of Whole Genome Sequencing (WGS)? How is Venofer (iron sucrose) given? other treatments you receive, you will need to go back for several treatments with Venofer. Selected from data included with permission and copyrighted by First Databank, Inc. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Injectafer and Venofer are both brand-name drugs. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. If you have questions about side effects, call your doctor. Pain in your limbs. Drug class: Iron products. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. For more information about Injectafers approved uses, see the section Injectafer uses below. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. An iron infusion is a way to increase the body's iron levels quickly. But keep in mind that in this study, delayed allergic reaction only occurred in one person. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y The researchers looked to see how well each drug worked to increase peoples hemoglobin level. The Injectafer dosage your doctor prescribes will depend on your body weight. With IDA, you have low hemoglobin levels. Is Venofer Safe in Breastfeeding - Drlact.com Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. 2005 - 2023 WebMD LLC. This medicine may cause serious types . You will be watched closely by your doctor for 30 minutes after each dose. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. There are different types of anemia, but IDA is the most common type. And this can affect how well those parts of your body are able to work. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Serious side effects should be reported to a physician and/or PharmD for medical advice. As with all medications, the cost of Injectafer can vary. experience severe side effects, please seek medical attention right away and notify the ordering physician. For people with certain medical implants, such as pacemakers, an MRI may pose an . The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Their medical staff can help you set up another time to receive your Injectafer dose. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Injectafer contains the active drug ferric carboxymaltose. Severeside effectsmay end up causing a lot of disruption in a persons life. Version: 7.01. Infusion times range from less than 20 minutes to up to 4 hours. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. But for other people, doing so could lead to having too much iron in their body. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. And this person had gotten their first dose of the drug without having an allergic reaction. We cancelled my 5th because of the reaction. Iron infusion side effects vary depending on which form is being used. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Venofer pregnancy and breastfeeding warnings. Find out what health conditions may be a health risk when taken with Venofer Vial Have blood work checked as you have been told by the doctor. upper respiratory infection. And theyll recommend how soon after starting the drug you need to have this level checked. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. In the first group, some people continued taking iron by mouth, while other people took Injectafer. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Side effectsare uncomfortable reactions to medications or drugs. But for other people, their anemia may come back after Injectafer treatment. Injectafer is a brand-name prescription drug. Keep all medications away from children and pets. These side effects can range from being mild to severe. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Venofer injection contains iron sucrose, a form of the mineral iron. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. PDF Protocol for the use of Intravenous Iron Sucrose (Venofer Feraheme also comes as a liquid thats given by IV infusion. This includes your doctors, nurses, pharmacists, and dentists. Consult your doctor before breast-feeding. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Many patients with kidney disease cannot get enough iron from food and require injections. Consult the product instructions and your pharmacist for storage details. reactions at the site of the injection. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. It belongs to a class of medications called iron replacement products. What is Venofer? Depending on your anemia symptoms, your weight changes may be different than those described here. Notify your healthcare provider of any irritation at the injection site. Do not start, stop, or change the dose of any drug without checking with your doctor. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. No, Injectafer itself wont make you gain weight. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Venofer Side Effects. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Use Venofer as ordered by your doctor. You may report side effects to FDA at 1-800-FDA-1088. Vomiting. Its not known how common delayed allergic reaction might be in other people using Injectafer. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Iron sucrose can also be mixed in a. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Generics tend to cost less than brand-name drugs. This website is intended for use by US patients. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Call your doctor for medical advice about side effects. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Cancer patients who have anemia and are taking an ESA. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. %PDF-1.3 Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList Potential injection site discoloration has happened. MNT is the registered trade mark of Healthline Media. Brand-name medications usually cost more than generics. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Nose or throat irritation. Data on file, American Regent, Inc. 1. You may also need to monitor your blood pressure at home. (Hemoglobin is a protein thats found in red blood cells.). It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. These are not all the side effects that may occur; contact your healthcare provider if you have questions. . Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. All rights reserved. Remember that it is best to get your vitamins and minerals from food whenever possible. Learn about uses, cost, how it works, and more. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. If these effects continue or worsen, tell your doctor. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Allergic reactions typically occur the first time your body is exposed to a drug. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Injectafer isnt a medication that youll take regularly on a schedule. As a result, you may not make as much EPO as usual. Tell your doctor if you are pregnant or plan to become pregnant. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Yes, in some cases it may. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Not all possible drug interactions are listed here. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. What are the side effects of Venofer? Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Throw away unused or expired drugs. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] The infusion will take between 15-30 minutes if it is given in. Following an LSD trip, users may experience a sort of 'comedown.'. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. <> <> (A class of medications describes a group of drugs that work in the same way.). Pain, swelling, or redness at the injection site may occur. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. All of the people took iron by mouth for 2 weeks. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Side effects of HRT | Stella Iron infusion benefits. Side effectswill last a very long time if the cause of them is not resolved. Innovators Monograph Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Injectafer begins working as soon as it enters your body. Venofer (iron sucrose) dosing, indications, interactions, adverse Venofer: Uses, Taking, Side Effects, Warnings - Medicine.com Call your doctor right away if you have serious side effects.
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